Mutabilis

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Name
Mutabilis
About
Romainville, France
Current Development Stage
Lead optimization
REPAIR Impact Fund Investment
USD 8 million
Company Website
www.mutabilis.fr

Gram-negative

Mutabilis is a biotechnology company focused on the development of novel chemical entities to treat MDR Gram-negative bacterial infections. Mutabilis’ team has a unique expertise in diazabicyclooctane chemistry and its applications in the discovery of novel antibacterials and beta-lactamase inhibitors, inherited from the former Novexel company that contributed to the development of Avibactam. With outstanding stability to hydrolysis by serine- and metallo-beta-lactamases, diazabicyclooctane derivatives are particularly promising to address the most difficult infections, namely those that are resistant to carbapenems.